Distribution and Characterization of Progenitor Cells within the Human Filum Terminale

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Distribution and Characterization of Progenitor Cells within the Human Filum Terminale

BACKGROUND Filum terminale (FT) is a structure that is intimately associated with conus medullaris, the most caudal part of the spinal cord. It is well documented that certain regions of the adult human central nervous system contains undifferentiated, progenitor cells or multipotent precursors. The primary objective of this study was to describe the distribution and progenitor features of this...

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Characterization of the Filum terminale as a neural progenitor cell niche in both rats and humans

Neural stem cells (NSCs) reside in a unique microenvironment within the central nervous system (CNS) called the NSC niche. Although they are relatively rare, niches have been previously characterized in both the brain and spinal cord of adult animals. Recently, another potential NSC niche has been identified in the filum terminale (FT), which is a thin band of tissue at the caudal end of the sp...

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Incidental hemangioblastoma of the filum terminale.

Filum terminale hemangioblastoma is an extremely rare tumour with only a few case reports in the literature. The natural history is unknown but benign as well as more aggressive presentations have been reported. The authors present the first such lesion discovered incidentally and discuss the available literature.

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Myxopapillary ependymoma of filum terminale.

We report a case of 56-year-old patient suffering from myxopapillary ependymoma of filum terminale at the level of the fifth lumbar vertebra. The patient presented with progressive complaints of permanent pain in the anal and sacral region with duration of 8 months. When sneezing or attempting to do brisk movements, the pain irradiated to the posterior surface of the right thigh. Vertebral synd...

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Double myxopapillary ependymomas of the filum terminale.

intradural tumors (WHO grade I) that characteristically occur in the conus medullaris/filum terminale region. They are slow growing tumors with a good prognosis and long-term survival.1 We report a rare case of double MPE occurring at both extremities of the filum terminale. In the light of the present case and an extensive review of the literature, we summarize the imaging characteristics and ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2011

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0027393